When boat traffic makes it impossible to run lines, hunters must adjust tactics and abandon plans in order to fill their tags. One team returns after a two-year hiatus and decides to hunt a remote area that forces them to cross the dangerous shipping lanes of the mighty Mississippi River. Another team avoids bounty hunters and boat traffic by travelling to a new and remote area called Boudreaux's Run, while another team hunts a waterway riddled with swells from tugboats and barges.
